Edward Jenner vaccinating patients in the Smallpox and hhttps://wellcomecollection.org/works/dsu7wxauInoculation Hospital at St. Pancras: the patients develop features of cows. Coloured etching by J. Gillray, 1802., Welcome Museum Attribution-Non Commercial 4.0 International (CC BY-NC 4.0),https://creativecommons.org/licenses/by/4.0/
"Thousands of years ago, variola virus (smallpox virus) emerged and began causing illness and deaths in human populations, with smallpox outbreaks occurring from time to time. Thanks to the success of vaccination, the last natural outbreak of smallpox in the United States occurred in 1949. In 1980, the World Health Assembly declared smallpox eradicated (eliminated), and no cases of naturally occurring smallpox have happened since."
--https://www.cdc.gov/smallpox/index.html (accessed April 5, 2021)
The greatest killer : smallpox in history, with a new introduction by
Once known as the "great fire" or "spotted death," smallpox has been rivaled only by plague as a source of supreme terror. Although naturally occurring smallpox was eradicated in 1977, recent terrorist attacks in the United States have raised the possibility that someone might craft a deadly biological weapon from stocks of the virus that remain in known or perhaps unknown laboratories. In The Greatest Killer, Donald R. Hopkins provides a fascinating account of smallpox and its role in human history. Starting with its origins 10,000 years ago in Africa or Asia, Hopkins follows the disease through the ancient and modern worlds, showing how smallpox removed or temporarily incapacitated heads of state, halted or exacerbated wars, and devastated populations that had never been exposed to the disease. In Hopkins's history, smallpox was one of the most dangerous-and influential-factors that shaped the course of world events.
Slavery, Agriculture, and Malaria in the Arabian Peninsula by
In Slavery, Agriculture, and Malaria in the Arabian Peninsula, Benjamin Reilly illuminates a previously unstudied phenomenon: the large-scale employment of people of African ancestry as slaves in agricultural oases within the Arabian Peninsula. The key to understanding this unusual system, Reilly argues, is the prevalence of malaria within Arabian Peninsula oases and drainage basins, which rendered agricultural lands in Arabia extremely unhealthy for people without genetic or acquired resistance to malarial fevers. In this way, Arabian slave agriculture had unexpected similarities to slavery as practiced in the Caribbean and Brazil. This book synthesizes for the first time a body of historical and ethnographic data about slave-based agriculture in the Arabian Peninsula. Reilly uses an innovative methodology to analyze the limited historical record and a multidisciplinary approach to complicate our understandings of the nature of work in an area that is popularly thought of solely as desert. This work makes significant contributions both to the global literature on slavery and to the environmental history of the Middle East--an area that has thus far received little attention from scholars.
Surgeons, Smallpox, and the Poor by
Beginning with an account of the settlement of Halifax, Marble documents the care taken by the Lords of Trade and Plantations to provide proper food and health care during the settlers' passage across the Atlantic in May and June of 1749. He chronicles the rendezvous of regiments and ships in Halifax between 1755 and 1763, examining the two smallpox epidemics which followed their arrival. He deals with the treatment of the poor in Nova Scotia between the Seven Years War and the American Revolution, showing that many in this group were camp followers who had been abandoned by regiments that had left Halifax. Financial resources previously directed towards providing medical services for citizens had to be redirected to feed, clothe, and shelter such individuals. A third smallpox epidemic struck Nova Scotia in 1775-76 and, as Marble demonstrates, prevented the Americans from attacking Halifax. He examines the initial unsuccessful attempt to regulate the practice of medicine in Nova Scotia and explores the reasons the region lagged behind Lower Canada and the American colonies in this regard. Marble covers all aspects of health care, including hospitals, the training and practices of physicians and surgeons, the use of patent medicines, and the various types of medical and surgical treatments. As well, he has made a thorough study of individual patients through their wills, diaries, and personal letters.
The vaccination controversy : the rise, reign, and fall of compulsory vaccination for smallpox by
Smallpox was for several centuries one of the most deadly, most contagious and most feared of diseases, which goes some way towards explaining the controversy that surrounded nineteenth-century efforts to eradicate it. On one side were the authorities and medical men who were keen to put an end to the widespread ravages of smallpox by the most expedient means, while on the other side were ranged those parents who objected to the compulsory infliction on their children of a procedure that had no absolute guarantee of success, and that represented a gross invasion of private life. In this book, Stanley Williamson traces the origins of the vaccination controversy from the introduction from the Orient by Lady Mary Wortley Montague of the practice of inoculation, through the championing by Edward Jenner of the new method of vaccination using cowpox, and the successive Acts of Parliament that attempted to impose the practice on a sometimes recalcitrant populace. Using contemporary newspaper accounts and the writings of those close to the centre of the controversy, Williamson paints a vivid picture of the full-scale vaccination war that raged between the passage of the 1867 Compulsory Vaccination Act and the eventual relaxation of its demands just before the turn of the century. As well as offering a fascinating account of one of the earliest public health controversies, this book also raises issues relating to the balance between personal liberties and societal obligations that remain relevant for contemporary debates about infant vaccination.
The Life and Death of Smallpox by
"The most terrible of all the ministers of death." Thomas Macauley Mozart, Voltaire, Elizabeth I and Abraham Lincoln all had it--and survived. Millions did not. The scourge of smallpox affected rich and poor alike, killing many and disfiguring the rest. 'Cures' included bleeding, purging, oil of scorpions and even crabs' eyes. Edward Jenner's breakthrough in 1796 started the slow, often controversial, process of controlling the virus. By 1979 smallpox had become the first-ever disease to be eradicated. Yet, today, its possible use in biological warfare presents a major threat. This is an accessible account of the history, and possible future, of a terrifying disease. Ian Glynn is Professor of Physiology Emeritus at Cambridge University and Fellow of Trinity College. He is the author of An Anatomy of Thought (Oxford, 2000). Jenifer Glynn is a Cambridge historian and author of Tidings from Zion (Tauris, 2000).
Smallpox and the Literary Imagination, 1660-1820 by
Smallpox was a much feared disease until modern times, responsible for many deaths worldwide and reaching epidemic proportions amongst the British population in the seventeenth and eighteenth centuries. This book is a substantial critical study of the literary representation of the disease and its victims between the Restoration and the development of inoculation against smallpox around 1800. David Shuttleton draws upon a wide range of canonical texts including works by Dryden, Johnson, Steele, Goldsmith and Lady Mary Wortley Montagu, the latter having experimented with vaccination against smallpox. He reads these texts alongside medical treatises and the rare, but moving writings of smallpox survivors, showing how medical and imaginative writers developed a shared tradition of figurative tropes, myths and metaphors. This fascinating study uncovers the cultural impact of smallpox, and the different ways writers found to come to terms with the terror of disease and death.
The War Against Smallpox by
Michael Bennett provides the first history of the global spread of vaccination during the Napoleonic Wars, offering a new assessment of the cowpox discovery and Edward Jenner's achievement in making cowpox inoculation a viable and universally available practice. He explores the networks that took the vaccine around the world, and the reception and establishment of vaccination among peoples in all corners of the globe. His focus is on the human story of the horrors of smallpox, the hopes invested in vaccination by medical men and parents, the children put arm-to-arm across the world, and the early challenges, successes and disappointments. He presents vaccination as a quiet revolution, genuinely emancipatory, but also the sharp end of growing state power. By the end of the war in 1815, millions of children had been vaccinated. The early success of the war against smallpox paved the way to further advances towards eradication.
Rationalizing epidemics : meanings and uses of American Indian mortality since 1600 by
Ever since their arrival in North America, European colonists and their descendants have struggled to explain the epidemics that decimated native populations. Century after century, they tried to understand the causes of epidemics, the vulnerability of American Indians, and the persistence of health disparities. They confronted their own responsibility for the epidemics, accepted the obligation to intervene, and imposed social and medical reforms to improve conditions. In Rationalizing Epidemics, David Jones examines crucial episodes in this history: Puritan responses to Indian depopulation in the seventeenth century; attempts to spread or prevent smallpox on the Western frontier in the eighteenth and nineteenth centuries; tuberculosis campaigns on the Sioux reservations from 1870 until 1910; and programs to test new antibiotics and implement modern medicine on the Navajo reservation in the 1950s. These encounters were always complex. Colonists, traders, physicians, and bureaucrats often saw epidemics as markers of social injustice and worked to improve Indians' health. At the same time, they exploited epidemics to obtain land, fur, and research subjects, and used health disparities as grounds for "civilizing" American Indians. Revealing the economic and political patterns that link these cases, Jones provides insight into the dilemmas of modern health policy in which desire and action stand alongside indifference and inaction. Table of Contents: List of Figures Acknowledgments Introduction 1. Expecting Providence 2. Meanings of Depopulation 3. Frontiers of Smallpox 4. Using Smallpox 5. Race to Extinction 6. Impossible Responsibilities 7. Pursuit of Efficacy 8. Experiments at Many Farms Epilogue and Conclusions Notes Index Rationalizing Epidemics is a superb work of scholarship. By contextualizing his deep and thorough research in original documents within the larger literature on the history and nature of epidemics, Jones has produced a profound account of how epidemics are social and cultural phenomena, not just biological. This book will be of great interest to scholars of American Indian history and the history of medicine, and with its engaging and accessible writing style, it promises to be a book that students and the general public will appreciate as well. --Nancy Shoemaker, University of Connecticut An imaginative and insightful approach to health and disease among American Indians, Rationalizing Epidemics represents a remarkable accomplishment. The breadth of reading and depth of research, the subtlety used in explaining each case, and the original approach to the material are altogether impressive. Jones's book undoubtedly will be a major contribution to American history. --Daniel H. Usner, Jr., Vanderbilt University
Rotting face : Smallpox and the American Indian by
The smallpox epidemic of 1837-1838 forever changed the tribes of the Northern Plains.a Before it ran out of human fuel, the disease claimed 20,000 souls.a R.G. Robertson tells the story of this deadly virus with modern implications. "
The vaccinators : smallpox, medical knowledge, and the "opening" of Japan by
In Japan, as late as the mid-nineteenth century, smallpox claimed the lives of an estimated twenty percent of all children born--most of them before the age of five. When the apathetic Tokugawa shogunate failed to respond, Japanese physicians, learned in Western medicine and medical technology, became the primary disseminators of Jennerian vaccination--a new medical technology to prevent smallpox. Tracing its origins from rural England, Jannetta investigates the transmission of Jennerian vaccination to and throughout pre-Meiji Japan. Relying on Dutch, Japanese, Russian, and English sources, the book treats Japanese physicians as leading agents of social and institutional change, showing how they used traditional strategies involving scholarship, marriage, and adoption to forge new local, national, and international networks in the first half of the nineteenth century. The Vaccinators details the appalling cost of Japan's almost 300-year isolation and examines in depth a nation on the cusp of political and social upheaval.
House on fire : the fight to eradicate smallpox by
A story of courage and risk-taking, House on Fire tells how smallpox, a disease that killed, blinded, and scarred millions over centuries of human history, was completely eradicated in a spectacular triumph of medicine and public health. Part autobiography, part mystery, the story is told by a man who was one of the architects of a radical vaccination scheme that became a key strategy in ending the horrible disease when it was finally contained in India. In House on Fire, William H. Foege describes his own experiences in public health and details the remarkable program that involved people from countries around the world in pursuit of a single objective--eliminating smallpox forever. Rich with the details of everyday life, as well as a few adventures, House on Fire gives an intimate sense of what it is like to work on the ground in some of the world's most impoverished countries--and tells what it is like to contribute to programs that really do change the world.
The End of a Global Pox: America and the eradication of smallpox in the Cold War era by
By the mid-twentieth century, smallpox had vanished from North America and Europe but continued to persist throughout Africa, Asia, and South America. In 1965, the United States joined an international effort to eradicate the disease, and after fifteen years of steady progress, the effort succeeded. Bob H. Reinhardt demonstrates that the fight against smallpox drew American liberals into new and complex relationships in the global Cold War, as he narrates the history of the only cooperative international effort to successfully eliminate a human disease. Unlike other works that have chronicled the fight against smallpox by offering a "biography" of the disease or employing a triumphalist narrative of a public health victory, The End of a Global Pox examines the eradication program as a complex exercise of American power. Reinhardt draws on methods from environmental, medical, and political history to interpret the global eradication effort as an extension of U.S. technological, medical, and political power. This book demonstrates the far-reaching manifestations of American liberalism and Cold War ideology and sheds new light on the history of global public health and development.
Jenner on Trial: ethical examination of vaccine research in the age of smallpox and the age of AIDS by
This book examines how an Ethics Review Committee using today's ethical standards as articulated in The Nuremberg Code, and the WHO/CIOMS International Ethical Guidelines for Biomedical Research Involving Human Subjects, might assess the scientific and ethical design of Edward Jenner's first experimental vaccine experiment. It explores the potential risks and benefits to young James, the adequacy of the preliminary evidence that Jenner used to justify performing his experiment, and how he might have complied with requirements for informed consent. In addition to its historical interest for 18th century England and for the origins of today's biomedical research ethics standards, the book is significant as a case study in the ethics of basic vaccine research. It thus raises relevant questions about today's vaccine research, particularly relating to HIV.
Smallpox: the fight to eradicate a global scourge by
Though smallpox was eradicated from the planet two decades ago, recent terrorist acts have raised the horrific possibility that rogue states, laboratories, or terrorist groups are in possession of secret stockpiles of the virus that causes the disease, and may be preparing to unleash it on target populations. Because it is a far deadlier killer than other biological warfare agents such as anthrax, and because the universal vaccination against smallpox was halted decades ago, a smallpox attack today would be nothing short of catastrophic. This clear, authoritative study looks at the long and fascinating history of the virus, with an informative overview of the political, biological, environmental, medical, and legal issues surrounding the question of whether or not the virus should be exterminated. The only two known samples of the virus are currently stored in Atlanta and Russia. The World Health Organization has repeatedly scheduled their destruction--an action that would rid the planet of all publicly acknowledged smallpox strains forever. Opponents of this plan argue that by destroying these last samples we are denying the possibility that this unique virus could be turned to beneficial purposes in basic scientific research. Others see the stockpile as part of a deterrent against future germ attacks. Proponents of prompt eradication argue that scientists have already learned all they can from this particular virus, and that by destroying the stockpile we are preventing it from ever falling into the wrong hands. As a thirty-year veteran of arms control issues, David Koplow is uniquely suited to provide readers with an informed and well-considered understanding of the complexities involved in the handling of this deadly virus.
